KMID : 0877220010050020177
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Journal of Korean Epilepsy Society 2001 Volume.5 No. 2 p.177 ~ p.185
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The Evaluation of the Quality of Life in Epileptic Patients : The Study of QOLIE(Quality of Life in Epilepsy)-89
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Kim Joon-Tae
Shin Dae-Su Kim Jong-Ki Hwang In-Yong Choi Seong-Min Kim Byeong-Chae Kim Myeong-Kyu Cho Ki-Hyun
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Abstract
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Purpose: Patients with epilepsy experience the impairment of Quality of life (QOL). The objective of this study was to investigate the ¡¯Quality of Life¡¯ in epileptic patients and the influences of clinical factors upon QOL in epileptic patients.
Methods: Total 138 epileptic patients (male : 77, female : 61) were recruited for the study. The Quality of Life in Epilepsy (QOLIE)-89 was applied to evaluate QOL in epileptic patients. We gathered data about clinical variables (seizure type, frequency, duration of disease, number of antiepileptic drug, and depression) and socio-demographic variables (age, sex, marriage, employment, and education), and compared each variables in use of QOLIE-89 score.
Results: Depression influenced negatively the most of all subscales (16 of 20 subscales) and overall score (p<0.01), and was the most significant inverse predictor of QOL in patients with epilepsy. Patients who were seizure-free in the past year reported better QOL than those with seizure-doing (p<0.05). Patients with polypharmacy showed lower scores at overall QOL, health discouragement, language, and overall score than those with monopharmacy (p<0.05). Male showed lower score than female at the scale of sexual relation (p<0.05), but higher scores at scales of health perception, overall health, and physical health (p<0.05). Highly-educated group (> or =16 year) had higher score at overall score and emotional well-being (p<0.05). However, age, marital state, employment, seizure type, and duration of disease did not affect QOL significantly.
Conclusions: Sex, education, number of AEDs, depression, and seizure free state were major socio-clinical factors affecting QOL in patients with epilepsy. It is suggested that physician should recognize these factors and manage appropriately for improving the QOL.
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KEYWORD
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Epilepsy, Quality of life, QOLIE-89, Depression, Seizure free state
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